LORENZO PEREZ, NORAILYS,MORERA CORDOVA, VIVIAN,DOMANGUEZ HORTA, MARAA DEL CARMEN,PADRA³N PALOMARES, GABRIEL RAMA³N,LA³PEZ MARAN, NELIA,BARBERA¡ BETANCOURT, ARIANA,HERNA¡NDEZ GARCAA, ARIADNA,COSME
申请号：
DK10189769
公开号：
DK2371847T3
申请日:
2005.09.22
申请国别(地区):
DK
年份:
2014
代理人:
摘要：
Peptides of human heat shock protein of 60 kDa, that constitute epitopes for T cells, as well as their derived peptides, which are modified at the contact sites with the MHC molecule, are useful to induce mechanisms of peripheral tolerance, in particular mechanisms of anergy or mediated by clones of regulatory T cells in patients with Rheumatoid Arthritis. The invention also refers pharmaceutical compositions comprising such peptides for the treatment of Rheumatoid Arthritis.
