CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CIGB)
发明人:
DOMOENGUEZ HORTA, MARIA DEL CARMEN,PADRAN PALOMARES, GABRIEL R.,LAPEZ MAROEN, NELIA,LORENZO PEREZ, NORAILYS,BARBERA BETANCOURT, ARIANA,HERNANDEZ GARCOEA, ARIADNA,MORERA CORDOVA, VIVIAN,COSME DOEAZ, CA
申请号：
AT05794474
公开号：
AT546462T
申请日:
2005.09.22
申请国别(地区):
AT
年份:
2012
代理人:
摘要：
Peptides of human heat shock protein of 60 kDa, that constitute epitopes for T cells, as well as their derived peptides, which are modified at the contact sites with the MHC molecule, are useful to induce mechanisms of peripheral tolerance, in particular mechanisms of anergy or mediated by clones of regulatory T cells in patients with Rheumatoid Arthritis. The invention also refers pharmaceutical compositions comprising such peptides for the treatment of Rheumatoid Arthritis.
