CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CIGB)
发明人:
LORENZO PEREZ, NORAILYS,MORERA CORDOVA, VIVIAN,PADRON PALOMARES, GABRIEL R.,LOPEZ MARIN, NELIA,BARBERA BETANCOURT, ARIANA,HERNANDEZ GARCIA,VAZQUEZ BONACHEA,SUAREZ ALBA, JOSE,DOMINGUEZ HORTA, MARIA DEL
申请号：
DK05794474
公开号：
DK1803732T3
申请日:
2005.09.22
申请国别(地区):
DK
年份:
2012
代理人:
摘要：
Peptides of human heat shock protein of 60 kDa, that constitute epitopes for T cells, as well as their derived peptides, which are modified at the contact sites with the MHC molecule, are useful to induce mechanisms of peripheral tolerance, in particular mechanisms of anergy or mediated by clones of regulatory T cells in patients with Rheumatoid Arthritis. The invention also refers pharmaceutical compositions comprising such peptides for the treatment of Rheumatoid Arthritis.
