RUIZ, JUAN,SELLOS-MOURA, MARCIA,CONCINO, MICHAEL, F.,PAN, LUYING,MARTINI, PAOLO,STRACK-LOGUE, BETTINA,ALDERUCCI, SCOTT
申请号:
EP11810304
公开号:
EP2595651A4
申请日:
2011.07.19
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Described herein are isolated nucleic acid molecules comprising nucleotide sequence encoding mannose receptor, C type 1 (MRC1) wherein the 5′ region of the nucleotide sequence encoding MRC1 is codon optimized; cells comprising such nucleic acid molecules; and methods of detecting antibody production, e.g., neutralizing antibody production, in a subject being treated for Gaucher disease using such cells.