Michael F. Concino;Marcia Sellos-Moura;Scott Alderucci;Juan Ruiz;Paolo Martini;Bettina Strack-Logue;Pan Luying
发明人:
Juan Ruiz,Marcia Sellos-Moura,Michael F. Concino,Pan Luying,Paolo Martini,Bettina Strack-Logue,Scott Alderucci
申请号：
US13811122
公开号：
US09453847B2
申请日:
2011.07.19
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Described herein are isolated nucleic acid molecules comprising nucleotide sequence encoding mannose receptor, C type 1 (MRC1) wherein the 5′ region of the nucleotide sequence encoding MRC1 is codon optimized； cells comprising such nucleic acid molecules； and methods of detecting antibody production, e.g., neutralizing antibody production, in a subject being treated for Gaucher disease using such cells.
