Muhammad ALTAF,Muhammad MONIM-UL-MEHBOOB,Anvarhusein Abdulkadir ISAB,Saleh ALTUWAIJRI
申请号:
US14990509
公开号:
US20170197997A1
申请日:
2016.01.07
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Monomeric and dimeric gold(I) complexes as anticancer agents. The gold(I) complexes are coordinated to mixed ligands: one phosphine-based ligand that may be monodentate or bidentate and at least one dithiocarbamate-based ligand that is monodentate. Pharmaceutical compositions incorporating the gold(I) complexes, methods of synthesis, methods of treating cancer and methods of inhibiting cancer cell proliferation and inducing cancer cell apoptosis are also provided.