WU LEE, YAN HWA,吴妍华,吳妍華,LIU, DEAN-MO,刘典谟,劉典謨,HUANG, WEI-TING,黄唯婷,黃唯婷,MAI, RU-TSUN,麦如村,麥如村,CHEN, YI-HSIN,陈以欣,陳以欣
申请号:
TW108118072
公开号:
TWI705813B
申请日:
2019.05.24
申请国别(地区):
TW
年份:
2020
代理人:
摘要:
Disclosed herein is a ganetespib-containing particle, which includes an active ingredient selected from ganetespib, a pharmaceutically acceptable salt of ganetespib, and a combination thereof, and an amphiphilic chitosan-based carrier carrying the active ingredient. Also disclosed herein are a pharmaceutical composition including the ganetespib-containing particle, and use of such pharmaceutical composition in treating cancer.本發明揭示一含有ganetespib的粒子,其包括一選自於下列的活性成分:ganetespib、ganetespib的一藥學上可接受的鹽類,以及它們的組合;以及一以兩親幾丁聚醣為基礎的載體,其攜帶該活性成分。本發明亦揭示一藥學組成物,其包括該含有ganetespib的粒子,以及該藥學組成物在治療癌症上的用途。