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Imidazothiadiazole and imidazopyridazine derivatives as protease activated receptor 4 (PAR4) inhibitors for treating platelet aggregation
专利权人:
发明人:
Alain Martel,François Tremblay,Anne Marinier,Eldon Scott Priestley,Shoshana L. Posy,R. Michael Lawrence,Michael M. Miller
申请号:
US14396831
公开号:
US09518064B2
申请日:
2013.04.24
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides imidazothiadiazole compounds of Formula (I) Wherein W, Y, R0, R2, R4, Ra, Rb, X1, X2, X3 and X4 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.
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