BRISTOL-MYERS SQUIBB COMPANY;UNIVERSITÉ DE MONTRÉAL
发明人:
Jacques Banville,Roger Remillard,Edward H. Ruediger,Daniel H. Deon,Marc Gagnon,Laurence Dube,Julia Guy,Eldon Scott Priestley,Shoshana L. Posy,Brad D. Maxwell,Pancras C. Wong,R. Michael Lawrence,Michae
申请号:
US16538917
公开号:
US20200123160A1
申请日:
2019.08.13
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides thiazole compounds of Formula Iwherein W, Y,R0, R2, R4, R5, R6, R7, X1, X2, X3 and X4 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.