Erickson, Hans K.,Steeves, Rita,Kovtun, Yelena V.,Chari, Ravi V. J.,Lutz, Robert J.,Goldmakher, Viktor S.,Lambert, John M.
申请号:
AU2006236489
公开号:
AU2006236489C1
申请日:
2006.04.14
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Methods of killing or inhibiting tumors comprising of heterogeneous or mixed cellpopulations is described. The killing or inhibition of tumors is achieved byselectively targeting a unique ligand suspected of being expressed on a particular cellpopulation to also kill a cell population lacking the unique ligand. These conjugateshave therapeutic use as they are delivered to a specific cell population to killthese cells and the cytotoxic drug is released to kill non-targeted cells, therebyeliminating the tumor.