Viktor S. Goldmakher,Robert J. Lutz,Ravi V. J. Chari,Yelena V. Kovtun,John M. Lambert,Rita Steeves,Hans K. Erickson,Wayne C. Widdison
申请号：
US13229422
公开号：
US08388960B2
申请日:
2011.09.09
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Methods of killing or inhibiting tumors comprising of heterogeneous or mixed cell populations is described. The killing or inhibition of tumors is achieved by selectively targeting a unique ligand suspected of being expressed on a particular cell population to also kill a cell population lacking the unique ligand. These conjugates have therapeutic use as they are delivered to a specific cell population to kill these cells and the cytotoxic drug is released to kill non-targeted cells, thereby eliminating the tumor.
