Viktor S. Goldmakher,Robert J. Lutz,Ravi V. J. Chari,Yelena V. Kovtun,John M. Lambert,Rita Steeves,Hans K. Erickson
申请号：
US12186411
公开号：
US08137669B2
申请日:
2008.08.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Methods of killing or inhibiting tumors comprising of heterogeneous or mixed cell populations is described. The killing or inhibition of tumors is achieved by selectively targeting a unique ligand suspected of being expressed on a particular cell population to also kill a cell population lacking the unique ligand. These conjugates have therapeutic use as they are delivered to a specific cell population to kill these cells and the cytotoxic drug is released to kill non-targeted cells, thereby eliminating the tumor.
