2. Compounds from 7-(isobutene-amine)-6,7,8,9-tetrahydropyridine [1,2-a] of Indian acrylic acid, regulator of prostaglandin D2 receptor; drug synthesis; for the prevention and treatment of allergic and immunological diseases, such as asthma.
The present invention relates to 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives of the formula (I), wherein R1, R2, R3 and R4 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.COMPUESTOS DERIVADOS DEL ACIDO 7-(HETEROARIL-AMINO)-6,7,8,9-TETRAHIDROPIRIDO[1,2-A]INDOL ACETICO, MODULADORES DEL RECEPTOR DE PROSTAGLANDINA D2; COMPOSICION FARMACEUTICA; Y USO EN LA PREVENCION Y EL TRATAMIENTO DE ENFERMEDADES ALERGICAS E INMUNES TALES COMO ASMA.