An aerosolization mitigation device is provided. The aerosolization mitigation device can include a negative pressure aerosolization mitigation system. A transparent barrier can form a frame of the system, and a negative pressure can be generated in the internal volume. The device can isolate a patient to allow ambulatory, surgical, and routine care to proceed during periods of higher patient volume or viral transmission. The negative pressure environment mitigates viral transmission to protect healthcare providers and others in the vicinity of the patient from health risks during patient care.
