Jin Kim MONTCLARE,Haresh T. MORE,Joseph FREZZO,Carlo YUVIENCO
申请号：
US14910794
公开号：
US20160185834A1
申请日:
2014.08.11
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Provided are compositions and methods for efficient delivery of polynucleotides and/or small molecules to or into cells. The compositions comprises a peptide which as an excess positive charge and self assembles into homopentamers. The homopentamers can non-covalently bind polynucleotides. When encapsulated in lipid systems, such as liposomes, the lipoproteoplexes so formed, are capable of delivering both nucleic acids and small molecules to cells.
