Luca DE STEFANO,Ilaria REA,Principia DARDANO,Luigi NICOLAIS
申请号:
US16610526
公开号:
US20200086102A1
申请日:
2018.04.06
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The object of the present invention is a device (1) for the transdermal delivery of active molecules. The device (1) comprises a support element (8) and a plurality of micro-needles (10) that protrude from a first surface of the support element (8), the support element (8) and the micro-needles (10) being both permeable to the active molecules. The device (1) further comprises a porous membrane (7) configured to be loaded with said active molecules, which lies on a second surface of the support element (8). Characteristically, the porous membrane (7) is configured to behave, from an optical viewpoint, as a Bragg mirror. Further objects of the present invention are the following uses of the device (1): for monitoring the release and/or the decay of the active molecules, for the optical control of the release of the active molecules and for the thermal control of the release of the active molecules. Lastly, an object of the present invention is the method for producing the device (1) for transdermal delivery of active molecules.