Palmer, Brian Desmond,Ching, Lai Ming,Gamage, Swarnalatha Akuratiya
申请号：
AU2020203116
公开号：
AU2020203116A1
申请日:
2020.05.12
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
#$%^&*AU2020203116A120200528.pdf#####88 Abstract N-R10 XN~ N I Pharmaceutical compositions comprising 3-aminoisoxazolopyridine compounds of the 5 Formula I having IDO1 and/or TDO inhibitory activity are described, where W is CR', N or N-oxide； X is CR2 , N or N-oxide； Y is CR3, N or N-oxide； Z is CR4 , N or N-oxide； and at least one of W, X, Y, and Z is N or N-oxide； and R9 and RIO are as defined. Also described are methods of using such compounds in the treatment of various conditions, such as cancer. 10
