JORGE CARRILLO MOLINA,BONAVENTURA CLOTET SALA,JULIA M. BLANCO ARBUES
申请号：
US16612727
公开号：
US20200157192A1
申请日:
2018.05.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Fc-fusion protein derivatives against HIV have enhanced yield in mammalian cells, and extended antiviral and immunomodulatory activities. The Fc-fusion protein derivatives can block the entry of human immunodeficiency virus (HIV) into host cells, elicit effector functions through the activation of natural killer (NK) and other immune system cells, can be produced with high yield in mammalian cells, and have extended activity in vivo. Nucleic acids, vectors and host cells can express the Fc-fusion protein derivatives, which have therapeutic and diagnostic applications in human health.
