Aaron Craig BURNS,Michael Raymond COLLINS,Samantha Elizabeth GREASLEY,Robert Louis Hoffman,Peter Qinhua HUANG,Robert Steven Kania,Pei-Pei KUNG,Maria Angelica LINTON,Lakshmi Sourirajan NARASIMHAN,Paul
申请号：
US15826027
公开号：
US20180148441A1
申请日:
2017.11.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to compounds of formula (I)or pharmaceutically acceptable salts thereof, wherein A, L, D, R1-R15, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
