BURNS Aaron Craig,COLLINS Michael Raymond,GREASLEY Samantha Elizabeth,HOFFMAN Robert Louis,HUANG Qinhua,KANIA Robert Steven,KUNG Pei-Pei,LINTON Maria Angelica,NARASIMHAN Lakshmi Sourirajan,RICHARDSON
申请号:
SI201530998
公开号:
SI3137460T1
申请日:
2015.04.17
申请国别(地区):
SI
年份:
2019
代理人:
摘要:
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R-R, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.