BURNS, Aaron Craig,COLLINS, Michael Raymond,GREASLEY, Samantha Elizabeth,HOFFMAN, Robert Louis,HUANG, Qinhua,KANIA, Robert Steven,KUNG, Pei-Pei,LINTON, Maria Angelica,NARASIMHAN, Lakshmi Sourirajan,RI
申请号:
LT15726701
公开号:
LT3137460T
申请日:
2015.04.17
申请国别(地区):
LT
年份:
2019
代理人:
摘要:
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R-R, w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.