PROCÉDÉ DE TRAITEMENT DU CANCER PAR DES OLIGONUCLÉOTIDES ANTISENS CIBLANT PRDM15

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专利权人:

Agency for Science; Technology and Research

发明人:

GUCCIONE, Ernesto,WEE, Keng Boon, Dave

申请号：

EP17847101

公开号：

EP3506910A4

申请日:

2017.09.04

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention relates to antisense oligonucleotides for modulating the activity of PRDM15 and use thereof in the treatment of cancer. In particular, said antisense oligonucleotides are capable of inducing the skipping of an exon of a PRDM15 mRNA. The present invention also relates to a method for determining prognosis in a patient with cancer, or selecting a therapeutic strategy for a patient with cancer, by assessing the level of PRDM15 nucleic acid, protein or activity in a sample.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/