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增強抗分枝桿菌的活性抗生素活性的飽和的氮和N-醯化的雜環化合物
专利权人:
UNIVERSITE DE DROIT ET DE LA SANTE LILLE 2
发明人:
Nicolas WILLAND N,Benoit DEPREZ B,Alain BAULARD A,Priscille BRODIN P,Marion FLIPO M,Lucie MAINGOT L,‧維蘭德,‧德普雷,‧博拉爾,‧布魯丹,‧弗利波,‧曼戈
申请号:
HK16103219.1
公开号:
HK1215254A
申请日:
2016.03.18
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The present invention concerns a compound of general formula (I): in which n=0 or 1, R1 represents an optionally substituted alkyl chain, in particular substituted alkyl chain, in particular substituted with fluorine, X is chosen from N and CH, and R2 is chosen from optionally substituted phenyl and benzyl, wherein the heterocycles having 6 vertices comprise one, two or three nitrogen atoms. The present invention also concerns the use of this compound as a medicament, in particular in the treatment of bacterial and mycobacterial infections such as tuberculosis in combination with an antibiotic that is active against bacteria and/or mycobacteria, said compound potentiating the activity of said antibiotic.
来源网站:
中国工程科技知识中心
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