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SATURATED NITROGEN AND N-ACYLATED HETEROCYCLES POTENTIATING THE ACTIVITY OF AN ACTIVE ANTIBIOTIC AGAINST MYCOBACTERIA
专利权人:
UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2
发明人:
WILLAND, Nicolas,DEPREZ, Benoit,BAULARD, Alain,BRODIN, Priscille,FLIPO, Marion,MAINGOT, Lucie
申请号:
TN2015000202
公开号:
TN2015000202A1
申请日:
2015.05.25
申请国别(地区):
TN
年份:
2016
代理人:
摘要:
The present invention concerns a compound of general formula (I) in which n = 0 or 1, R1 represents an optionally substituted alkyl chain, in particular substituted with fluorine, X is chosen from N and CH, and R2 is chosen from phenyl and optionally substituted benzyl, and the heterocycles having 6 vertices comprising one, two or three nitrogen atoms. The present invention also concerns the use of this compound as a drug, in particular in the treatment of bacterial and mycobacterial infections such as tuberculosis in combination with an antibiotic that is active against bacteria and/or mycobacteria, said compound potentiating the activity of said antibiotic.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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