VALDES JOAQUIN MARIO,CHARTASH ELLIOT K.,BARCHUK WILLIAM T.,PAULSON SUSAN K.,GORDON KENNETH B.,AWNI WALID M.,BAO YANJUN,GLASS WILLIAM G.,GU YIHUA,HARRIS TOM C.,KAUL MARTIN,MULANI PARVEZ M.,NOERTERSHEUS
申请号:
NZ59872210
公开号:
NZ598722A
申请日:
2010.09.14
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is the use of an antibody, or antigen-binding portion thereof, which is capable of binding to the p40 subunit of IL-12 and/or IL-23, for the manufacture of a medicament in treating psoriasis in a subject by administering a first dose amount of about 180 mg to about 220 mg of the antibody, or antigen-binding portion thereof, to the subject at weeks 0 and 4, and administering a second dose amount of about 80 mg to about 120 mg of the antibody, or antigen-binding portion thereof, to the subject every 4 weeks thereafter.