A method of decreasing IL-6 level in a subject, comprising: identifying a subject in need thereof; and administering to the subject a composition that contains small cells that are greater than 2 micrometer s and less than 6 micrometer s in size; wherein the small cells include somatic stem cells that are (i) pluripotent; and (i) CD349(+), CD9(−), Oct4(+), Nanog(−), Lgr5(+), CD66e(+), CD133(+), or CD34(+).