SUMMARY OF THE INVENTION The present invention provides bone marrow-derived mesenchymal stem cells (GPR40) positive G-protein coupled receptor 40 which can be differentiated into nerve cells by the induction of polyunsaturated fatty acid (PUFA). In other words, the bone marrow-derived mesenchymal stem cells of GPR40-positive derived from a mammal, and CD29-positive, CD90-positive, CD73-positive, CD105-positive, CD3-negative, CD4-negative, CD8-negative, CD14-negative, CD34-negative, the present invention is CD45 negative further , it is a bone marrow-derived mesenchymal stem cells that are CD31 negative.本発明は多価不飽和脂肪酸(PUFA)の誘導により神経細胞に分化し得るG-protein coupled receptor 40(GPR40)陽性の骨髄由来間葉系幹細胞の提供を目的とする。すなわち、本発明は哺乳動物由来のGPR40陽性の骨髄由来間葉系幹細胞、及びさらにCD29陽性、CD90陽性、CD73陽性、CD105陽性、CD3陰性、CD4陰性、CD8陰性、CD14陰性、CD34陰性、CD45陰性、CD31陰性である骨髄由来間葉系幹細胞である。
