A method of increasing autophagy in a subject, comprising: identifying a subject in need thereof and administering to the subject a composition that contains small cells that are greater than 2 micrometers and less than 6 micrometers in size wherein the small cells include somatic stem cells that are (i) plurripotent or totipotent and (ii) CD349(+), CD9(+), Oct4(+), Nanog(+), Lgr5(+), CD66e(+), CD133(+), or CD34(+).一種在一個體中增加自體吞噬之方法,包含:辨識出有其需要之個體;以及投予一組成物至該個體,該組成物含有多個尺寸大於2微米且小於6微米之小細胞; 其中該等小細胞包括體幹細胞,其為(i)多潛能性的或全能性的;以及(ii) CD349(+)、CD9(+)、Oct4(+)、Nanog(+)、Lgr5(+)、CD66e(+)、CD133(+)、或CD34(+)。(無)
