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血糖値を降下させる物質の評価方法、スクリーニング方法及び製造方法
专利权人:
株式会社ゲノム創薬研究所
发明人:
関水 和久,浜本 洋,松本 靖彦,住谷 瑛理子,杉田 拓也
申请号:
JP2008178397
公开号:
JP5303209B2
申请日:
2008.07.08
申请国别(地区):
JP
年份:
2013
代理人:
摘要:

PROBLEM TO BE SOLVED: To provide cost-effective methods for accurately and excellently screening, evaluating and manufacturing diabetic curative drugs in which few ethical problems exist, additionally also cost-effective laboratory animals under specific condition to preferably be used in the above methods with few ethical problems.

SOLUTION: This is the method for evaluating as to whether a test substance is the matter which lowers human blood sugar level or not, characterized by comprising a process (a) to raise glucose (B) concentration in fat body or blood of a target invertebrate animal by allowing this invertebrate animal to ingest glucose (A), a process (b) to administer the above test substance to the target invertebrate animal with its glucose (B) concentration in fat body or blood increased which is obtained from the above process (a), and a process (c) to measure the glucose (B) concentration in fat body or blood of the invertebrate animal injected with the above test substance.

COPYRIGHT: (C)2009,JPO&INPIT

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