A one-hand device for an ocular irrigation and aspiration has a tube (3), which having a tip (5) at a front end, wherein the tip (5) has an irrigation fluid orifice outlet (5a) for the exit of the irrigation fluid and an aspiration opening (5b) for taking up the material to be extracted by suction. An irrigation fluid pump (11) is arranged in the tube (3) and is connected to the irrigation fluid orifice outlet (5a) via an irrigation conduit (115). In the tube (3) an aspiration pump (12) is arranged, which is connected to the aspiration opening (5b) via an aspiration conduit (125). A controller (13) regulates the flow rate through the irrigation conduit (115) such that it is equal to the flow rate through the aspiration conduit (125). Preferably a cutting tool/milling tool is rotatably mounted in the aspiration opening (5b).