THE UNITED STATES OF AMERICA; REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
SHANKER GUPTA
申请号:
PT16157001
公开号:
PT3078667T
申请日:
2002.01.25
申请国别(地区):
PT
年份:
2018
代理人:
摘要:
The present invention provides stable compounds prepared from boronic acid and lyophilized compounds thereof of formula (1) in which Z 1 and Z 2 are moieties derived from sugar. The invention also provides methods for preparing such compounds. Lyophilizing a mixture comprising a boronic acid compound and a moiety derived from sugar produces a stable composition that readily releases the boronic acid compound upon reconstitution in aqueous media.