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FORMULATION DES COMPOSÉS D'ACIDE BORONIQUE
专利权人:
THE UNITED STATES OF AMERICA; REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
申请号:
EP10006835.2
公开号:
EP2251344B1
申请日:
2002.01.25
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention provides stable compounds prepared from boronic acid and lyophilized compounds thereof of formula (1) in which Z 1 and Z 2 are moieties derived from sugar. The invention also provides methods for preparing such compounds. Lyophilizing a mixture comprising a boronic acid compound and a moiety derived from sugar produces a stable composition that readily releases the boronic acid compound upon reconstitution in aqueous media.
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