LAI, WEN FU T.,赖文福,賴文福,PAN, LI CHEM,潘力诚,潘力誠,LIM, PAU-YEE,林葆喜,林葆喜,OUNG, JUNG CHOU,翁荣洲,翁榮洲,CHEN, CHUN WEI,陈俊玮,陳俊瑋
申请号：
TW095103954
公开号：
TWI399227B
申请日:
2006.02.06
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
This invention relates to a bone implant that includes a bioinert substrate covered with a ceramic layer containing a plurality of indentations. The total surface area of the indentations is 30-70% of the total surface area of the ceramic layer. This invention also relates to a method of preparing such a bone implant. The method includes: (1) affixing a ceramic layer on the surface of a bioinnert substrate (2) forming a plurality of indentations in the ceramic layer, wherein the total surface area of the indentations in 30-70% of the total surface area of the ceramic layer and (3) immobilizing a biopolymer onto the ceramic layer via covalent bonding.本發明係有關於一種骨植入物,其包含一生物惰性基材(bioinert substrate)且塗覆著一層含有多個凹陷處(indentations)的陶瓷層。該等凹陷處的總表面積為該陶瓷層總表面積的30-70%。本發明亦有關於製造此類骨植入物的方法。該方法包括步驟:(1)將一陶瓷層附加在一生物惰性基材的表面上;(2)在該陶瓷層中形成多個凹陷處,其中該等凹陷處的總表面積為該陶瓷層總表面積的30-70%;以及(3)將一生物聚合物(biopolymer,或作生物高分子)藉由共價鍵結的方式固定在該陶瓷層上。
