Wen-Fu T. Lai,Li-Chern Pan,Pau-Yee Lim,Jung-Chou Oung,Chun-Wei Chen
申请号：
US11063074
公开号：
US08323348B2
申请日:
2005.02.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
This invention relates to a bone implant that includes a bioinert substrate covered with a ceramic layer containing a plurality of indentations. The total surface area of the indentations is 30-70% of the total surface area of the ceramic layer. This invention also relates to a method of preparing such a bone implant. The method includes: (1) affixing a ceramic layer on the surface of a bioinert substrate (2) forming a plurality of indentations in the ceramic layer, wherein the total surface area of the indentations is 30-70% of the total surface area of the ceramic layer and (3) immobilizing a biopolymer onto the ceramic layer via covalent bonding.
