ANIMAL DIFFERENT ANIMALS WITH A HUMANIZED SIGNAL REGULATORY PROTEIN GENE

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专利权人:

ИНК. (US);РЕГЕНЕРОН ФАРМАСЬЮТИКАЛС

发明人:

МЕРФИ Эндрю Дж. (US),ТЕРСТОН О. Гэвин (US),ВАРГХЕСЕ Бинду (US),ГУРЕР Каган (US)

申请号：

RU2016110462

公开号：

RU2016110462A

申请日:

2014.09.23

申请国别(地区):

RU

年份:

2017

代理人:

摘要：

Genetically modified non-human animals and methods and compositions for making and using the same are provided, wherein the genetic modification comprises a humanization of an endogenous signal-regulatory protein gene, in particular a humanization of a SIRP± gene. Genetically modified mice are described, including mice that express a human or humanized SIRP± protein from an endogenous SIRP± locus.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/