Ashok Vinayak Purandare,Kurt Zimmermann,Honghe Wan
申请号:
US15769113
公开号:
US20180305364A1
申请日:
2016.10.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
PRODRUGS OF IMIDAZOTRIAZINE COMPOUNDS AS CK2 INHIBITORS The invention provides pharmaceutically active compounds of formula (I) and prodrugs thereof. The formula (I) 2-(aminophenylamino)-4-amino-7-cyano-imidazo[2,1-f][1,2,4]triazine derivatives inhibit CK2 protein kinase activity, thereby making them useful for treating cancer, psoriasis and rheumatoid arthritis.