TUCKER, JOHN,SVIRIDOV, SERGEY,BRODSKY, LEONID,BURKHART, CATHERINE,PURMAL, ANDREI,GUROVA, KATERINA,GUDKOV, ANDREI
申请号：
ES09793304
公开号：
ES2402395T3
申请日:
2009.10.05
申请国别(地区):
ES
年份:
2013
代理人:
摘要：
A compound having a structural formula: ** FUn compound having a structural formula: ** ** Formula wherein R is selected from the group ormula wherein R ** is selected from the group consisting of hydrogen, C1- 6, haloalquique consisting of hydrogen, C1-6 alkyl, C1-6 haloalkyl, cycloalkyl, heterocycloalkyl, aryl, hlo C1-6, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, OR e, N (Re) 2 and SRe alternatively ceteroarilo, e, N (Re) 2 and SRe alternatively, either Ra and R1 or NRe and R1, togetherwith the átomualquiera of Ra and R1 or NRe and R1, togetherwith the carbon atoms to which they are attached form a years carbon to which they are attached form a heterocyclic ring carbocyclic or heterocyclic aliphatic or aliphatic carbocyclic cinillo cincoo six members Rb is selected from the group coo six members Rb is selected from the group consisting of hydrogen, C1-6 alkyl, haloalquique consisting of hydrogen, C1-6 alkyl, C1-6 haloalkyl, cycloalkyl, heterocycloalkyl, aryl, hlo C1-6, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, ORe , N (Re) 2 and SRe alternatively ceteroarilo, e, N (Re) 2 and SRe alternatively, either Rb and R6 or NRe and R6 togetherwith the átomualquiera Rb and R6 or NRe and R6 togetherwith the carbon atoms to which they are attached form a years carbon to which they are attached form a carbocyclic ring aliphatic carbocyclic five or five or aliphatic seismiembroillo seismiembros, or a heterocyclic or carbocyclic ring alifáts, or a heterocyclic ring or aliphatic carbocyclic five- or six members Rc is seleccionadoico five or six members Rc is selected from the group consisting of hydrogen, C1-6 group consisting of hydrogen alkyl, C1-6 alkyl, C1-6 hydroxyalkyl, cycloalkyl, heterocicloalq, C1-6 hydroxyalkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl and C ( > = O) Re, or Rc and Rd are Uilo, aryl, heteroaryl and C (> = O) Re, or Rc and Rd are taken together to form a alifátictoman ring together to form a ring alifáticode five, six or seven-membered opci
