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含天然活性胜肽粉末的腸溶膠囊劑型
专利权人:
PROTEIN BIOMEDICAL CORP.
发明人:
LEE, MORRIS,李守文,LEE, VICKY,李钰琦,李鈺琦,WU, EVA,吴伊凡,吳伊凡
申请号:
TW104220877
公开号:
TWM526402U
申请日:
2015.12.25
申请国别(地区):
TW
年份:
2016
代理人:
摘要:
The invention relates to a enteric coated capsule dosage form, which has a capsule shell, an enteric coating, which is wrapped in the capsule shell, wherein the enteric coating will not substantially crack or disintegrate at pH lt; 6.0, but will substantially crack or disintegrate at pH u2265 6.0, and a natural active peptide powder layer filled in the capsule shell.In this work, the physical barrier formed by the capsule shell is used to isolate the external water, air and light, and the enteric membrane is used to protect the capsule shell so that it will not dissolve in the acid gastric juice, but will start to disintegrate in the small intestine environment with neutral to alkaline pH value, so as to release the natural active peptide powder, so that the active components of the peptide can maintain their dimension during the transmission. It is active and stable.本創作關於一種腸溶膠囊劑型,其具有一膠囊外殼;一腸溶性膜衣,包覆於該膠囊外殼,其中該腸溶性膜衣在pH<;6.0下不會實質破裂或崩解,但在pH≧6.0時會實質破裂或崩解;以及被填充於該膠囊外殼內的天然活性胜肽粉末層。本創作藉由膠囊外殼所構成的物理性障壁來隔離外界的水份、空氣和光線,並且藉由腸溶性膜衣來保護膠囊外殼,使其在酸性的胃液中不會溶解,而在pH值中性至鹼性的小腸環境中才會開始崩解,以釋放出天然活性胜肽粉末,從而使得胜肽類活性成份在傳輸期間維持其活性和穩定性。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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