Michael Zamloot,Cherng-chyi Fu,De-Hwa Chou,Andrei Blasko,Su Il Yun
申请号：
US15099823
公开号：
US20160228367A1
申请日:
2016.04.15
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Novel compositions, formulations and dosage forms comprising stabilized micronizedopioid particles are disclosed. Exemplary opioids include oxycodone, oxymorphone, hydrocodone, and hydromorphone, including as free bases or as salts. Stabilized micronized opioid particles having a DV90 particle size distribution of less and or equal to 10μ or less than or equal to 20μ are disclosed. Methods for micronizing an opioid to provide stabilized micronized opioid particles are also disclosed.
