Micronized opioid compositions and dosage forms and methods of making same

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专利权人:

发明人:

申请号：

EP12192654.7

公开号：

EP2559428A1

申请日:

2008.12.05

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Novel compositions, formulations and dosage forms comprising stabilized micronized opioid particles are disclosed. Exemplary opioids include oxycodone, oxymorphone, hydrocodone, and hydromorphone, including as free bases or as salts. Stabilized micronized opioid particles having a DV90 particle size distribution of less and or equal to 10µ or less than or equal to 20µ are disclosed. Methods for micronizing an opioid to provide stabilized micronized opioid particles are also disclosed.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/