Joseph D. Kittle,Joel S. Lwande,Yuanyuan Tang,Shengwen Liang
申请号:
US16353337
公开号:
US20190284255A1
申请日:
2019.03.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A programmable receptor complex expressed by an immunocyte, wherein the programmable receptor complex includes a plurality of native or endogenously-expressed receptor subunits, wherein at least one of the plurality of native or endogenously-expressed receptor subunits has been engineered or modified to include an FcγRI receptor component or a biotin-binding component, and wherein the FcγRI receptor component or biotin-binding component is operative to bind to a target detector molecule that binds to or otherwise interacts with a predetermined target.