AELURI, MADHU,ALLINGHAM, JOHN,CRAIG, ANDREW,EVANS, ANDREW P.,GRANGE, REBECCA
申请号:
CA3073104
公开号:
CA3073104A1
申请日:
2018.08.17
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
A class of compounds useful in pharmaceutical compositions and methods for treating or preventing cancer is described. Analogs of Mycalolide B have been prepared and tested in breast and ovarian cancer cell lines. The compounds show utility for inhibition of survival and proliferation of tumor cells. The compounds have been shown to disrupt actin.