Rebecca Grange,John Allingham,Andrew Craig,P. Andrew Evans,Madhu Aeluri
申请号：
US16639207
公开号：
US20200306233A1
申请日:
2018.08.17
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A class of compounds useful in pharmaceutical compositions and methods for treating or preventing cancer is described. Analogs of Mycalolide B have been prepared and tested in breast and ovarian cancer cell lines. The compounds show utility for inhibition of survival and proliferation of tumor cells. The compounds have been shown to disrupt actin.
