N-methyl-2-[3-((e)-2-pyridin-2-yl-vinyl)-lh-indazol-6-ylsulfanyl]-benzamide for the treatment of chronic myelogenous leukemia

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专利权人:

发明人:

MURRAY BRION WILLIAM

申请号：

IN4739/DELNP/2014

公开号：

IN2014DN04739A

申请日:

2014.06.11

申请国别(地区):

IN

年份:

2015

代理人:

摘要：

The present invention relates to a method of treating chronic myelogenous leukemia in a subject comprising adminis o tering to the subject a compound, such as N-methyl-2-[3-((E)-2-pyridin-2-yl-vinyl)-lH-indazol-6-ylsulfanyl]-benzamide, that inhib - its the T3 15I mutation in BCR-ABL tyrosine kinase, or a pharmaceutically acceptable salt thereof. The present invention also relates o to a pharmaceutical composition comprising a compound such as N-methyl-2-[3-((E)-2-pyridin-2-yl-vinyl)-lH-indazol-6- ylsulfanyl]- benzamide, that inhibits the T3 151 mutation in BCR-ABL tyrosine kinase, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier or diluent.

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