ELIGLUSTAT (GENZ 112638) EN TANT QUE INHIBITEUR DE LA GLUCOSYLCÉRAMIDE SYNTHASE POUR L'UTILISATION DANS UN PROCÉDÉ POUR TRAITER LA MALADIE DE FABRY OU DE GAUCHER, LE PROCÉDÉ COMPRENANT AJUSTER LA DOSE INDIVIDUELLE AU MÉTABOLISME DU P-450 DU PATIENT

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专利权人:

Genzyme Corporation

发明人:

申请号：

EP16175117.7

公开号：

EP3133070B1

申请日:

2010.11.24

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The hemitartrate salt of a compound represented by the following structural formula: (Formula I Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described.

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