ELIGLUSTAT (GENZ 112638) COMO INIBIDOR DE GLICOSILCERAMIDA-SINTASE PARA UTILIZAÇÃO NUM MÉTODO DE TRATAMENTO DE DOENÇA DE FABRY OU DE GAUCHER, O MÉTODO COMPREENDENDO AJUSTAR A DOSE TERAPÊUTICA INDIVIDUAL AO METABOLISMO DO P-450 DO DOENTE
The hemitartrate salt of a compound represented by the following structural formula: (Formula I Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described.
