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COMPOSITION FOR ANTIBODY-DRUG CONJUGATE DIRECTED AGAINST TUMOR-CELL ASSOCIATED POLYSIALIC ACID
专利权人:
Cornell University
发明人:
Matthew P. DELISA,Emily C. COX,Christopher A. ALABI,Dana N. THORNLOW
申请号:
US16791509
公开号:
US20200277405A1
申请日:
2020.02.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present application discloses an immunoconjugate therapeutic comprising a polysialic acid targeting portion and an anti-cancer therapeutic coupled to the polysialic acid targeting portion. The present application also discloses methods of treating subjects with cancer and methods of targeting intracellular delivery of an anti-cancer therapeutic to a target cell population with the immunoconjugate therapeutic.
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