Systems and methods for detection and prevention of Return-Oriented-Programming (ROP) attacks in one or more applications, including an attack detection device and a stack inspection device for performing stack inspection to detect ROP gadgets in a stack. The stack inspection includes stack walking from a stack frame at a top of the stack toward a bottom of the stack to detect one or more failure conditions, determining whether a valid stack frame and return code address is present; and determining a failure condition type if no valid stack frame and return code is present, with Type III failure conditions indicating an ROP attack. The ROP attack is contained using a containment device, and the ROP gadgets detected in the stack during the ROP attack are analyzed using an attack analysis device.
