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COMPOUND HAVING PROTEIN TYROSINE PHOSPHATASE SHP-1 AGONIST ACTIVITY
专利权人:
发明人:
申请号:
EP16840834.2
公开号:
EP3345894A1
申请日:
2016.08.31
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
A compound having a chemical structure of formula I, wherein n is 0 or 1, X is N or C-R1, R1 is H or Cl, R2 and R3 are independently H, a halogen or an alkyl group, Ar is a substituted or unsubstituted phenylene or naphthylene group, with the substituted or unsubstituted phenylene group being A or B, and the naphthylene group being C, R4 is H, a halogen or an alkyl group, R5 is H, a halogen, an alkyl group, an alkoxyl group or a hydroxyl group, R6 is H or a hydroxyl group, and R7 is a substituted or unsubstituted aryl group. The compound has SHP-1 agonist activity, and can be used to treat cancer.
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