N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS

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专利权人:

INCYTE CORPORATION

发明人:

RODGERS JAMES D,ARVANITIS ARGYRIOS G,STORAGE LOUIS,SHAO LIXIN,GLENN JOSEPH P,SHEPARD STACEY,WANG HAISHENG,FOLMER BEVERLY,ZHU WENYU

申请号：

ZA201108544

公开号：

ZA201108544B

申请日:

2011.11.21

申请国别(地区):

ZA

年份:

2013

代理人:

摘要：

The present invention relates to N-(hetero)aryl-pyrrolidine derivatives of Formula I: which are JAK inhibitors, such as selective JAK1 inhibitors, useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, as well as cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/